High-Quality Antibody Production Services

High-quality antibody production services are an invaluable tool for scientific research, drug development, diagnostics, and therapeutics. Monoclonal antibodies are more specific than polyclonal antibodies and result from one clone of antibody cells that recognizes a single epitope on an antigen. This allows mAbs to produce highly reproducible results and are more tolerant of a wide range of experimental conditions (western blot/IP, ELISA etc.).

Characterizing the immunoglobulin class of an antibody can be done using a variety of methods such as sequencing the cDNA that encodes the immunoglobulin heavy chain or by performing mass spectrometry on purified antibodies collected from clonal populations of B cells. Depending on the intended application, this antibody characterization step can be critical in optimizing the performance of your custom antibody for the desired experiment or application.

High-Quality Antibody Production Services for Consistent Results

Choosing the right peptide antigen for your custom antibody project is essential to ensure that you get the best results possible. To increase the chance of getting a high-titer mAb, it is recommended that you choose a peptide that has hydrophilic regions that will be more accessible to the antibody binding site. Avoid peptides with secondary structures such as a-helices or b-sheets as these can inhibit antibody binding.

Sino Biological provides a full suite of antibody production services from custom peptide design to final antibody characterization and manufacture, including phage display, hybridoma, FACS-based Single B cell, and monoclonal antibody characterization. With our optimized in-house CHO and HEK293/CHO platforms, we can complete the high-throughput antibody production from gene to purified antibody as fast as two weeks.